tamoxifen is used to treat advanced breast cancer for 30 years and was a first-line endocrine therapy of choice for many more years. It is well tolerated and inexpensive, and serious side effects are rare. Survival rates are equal to those of chemotherapy, and although the initial response rates are lower, it offers superior quality of life in early responders. Tamoxifen should not be displaced as a key therapy for advanced breast cancer, without significant and convincing data from large randomized trials. Response rates depend on patient selection and are higher for patients with estrogen rapid tumor.
tamoxifen is used to treat advanced breast cancer for 30 years and was a first-line endocrine therapy of choice for many more years. It is well tolerated and inexpensive, and serious side effects are rare. Survival rates are equal to those of chemotherapy, and although the initial response rates are lower, it offers superior quality of life in early responders. Tamoxifen should not be displaced as a key therapy for advanced breast cancer, without significant and convincing data from large randomized trials. Response rates depend on patient selection and are higher for patients with estrogen rapid tumor.
...tamoxifen is used to treat advanced breast cancer for 30 years and was a first-line endocrine therapy of choice for many more years. It is well tolerated and inexpensive, and serious side effects are rare. Survival rates are equal to those of chemotherapy, and although the initial response rates are lower, it offers superior quality of life in early responders. Tamoxifen should not be displaced as a key therapy for advanced breast cancer, without significant and convincing data from large randomized trials. Response rates depend on patient selection and are higher for patients with estrogen rapid tumor.
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